On this episode, Dr. James Cox takes us on a deep dive into spinal manipulation and its effects on the immune system.

James M. Cox, DC, DACBR, FICC, Hon.D.Litt., FACO(H)

Dr. Cox is the developer of Cox® Technic Flexion Distraction Manipulation and the proud participant in the on-going federal research projects involving the National University of Health Sciences, Palmer College of Chiropractic Research Center, Loyola Stritch School of Medicine, University of Illinois, University of Iowa, Auburn University, etc. He is a member of the postgraduate faculty of the National University of Health Sciences and has been privileged to speak throughout the world.

Resources:

About Dr. Cox

curriculum vitae

More about Cox® Technic

www.coxtechnic.com

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The Cox 8 Table by Haven Medical

References:

·       Medeiros P1,2,3,4, de Freitas RL1,2,3,4,5, Boccella S1, Iannotta M1, Belardo C1, Mazzitelli M1, Romano R1, De Gregorio D6, Coimbra NC2,3,4, Palazzo E1, Maione S1.Characterization of the sensory, affective, cognitive, biochemical, and neuronal alterations in a modified chronic constriction injury model of neuropathic pain in mice. J Neurosci Res. 2019 Aug 8. doi: 10.1002/jnr.24501. [Epub ahead of print]

·       Colombi A1, Testa M2. The Effects Induced by Spinal Manipulative Therapy on the Immune and Endocrine Systems. Medicina (Kaunas). 2019 Aug 7;55(8). pii: E448. doi: 10.3390/medicina55080448.

·       Kedong H1, Wang D2, Sagaram M3, An HS4, Chee A5. Anti-inflammatory effects of interleukin-4 on intervertebral disc cells. The Spine Journal Volume 20, Issue 1, January 2020, Pages 60-68

·       Chen NF1,2,3, Chen WF1,4, Sung CS5,6, Lu CH2, Chen CL2, Hung HC1,7, Feng CW1,7, Chen CH1,7, Tsui KH8,9,10, Kuo HM11, Wang HD12,13,14, Wen ZH15,16,17, Huang SY18,19. Contributions of p38 and ERK to the antinociceptive effects of TGF-β1 in chronic constriction injury-induced neuropathic rats. J Headache Pain. 2016 Dec;17(1):72. Epub 2016 Aug 19.

·       Nemoto W, Yamada K, Ogata Y, Nakagawasai O, Onodera K, Sakurai H, Tan-No K. Chondroitin sulfate attenuates formalin-induced persistent tactile allodynia. J Pharmacol Sci Aug 5. pii: S1347-8613(16)30091-3. doi: 10.1016/j.jphs.2016.07.009.

·       Kemeny ME. The immune system: the mind-body connection.  Who gets sick and who stays well. Institute for Brain Potential, Po Box 2238, Los Banos Ca 93635

·       Egorova E1,2, Starinets A1,2, Tyrtyshnaia A1,2, Ponomarenko A1,2, Manzhulo I3,4. Hippocampal Neurogenesis in Conditions of Chronic Stress Induced by Sciatic Nerve Injury in the Rat. Cells Tissues Organs. 2019 Jul 8:1-11. doi: 10.1159/000501236. [Epub ahead of print]

·       Hingert D1, Nilsson J2, Barreto Henriksson H3,4, Baranto A3,4, Brisby H3,4.Pathological Effects of Cortisol on Intervertebral Disc Cells and Mesenchymal Stem Cells from Lower Back Pain Patients. Cells Tissues Organs. 2019 Jul 3:1-12. doi: 10.1159/000500772. [Epub ahead of print]

·       Kedong H1, Wang D2, Sagaram M3, An HS4, Chee A5. Anti-inflammatory effects of interleukin-4 on intervertebral disc cells. The Spine Journal Volume 20, Issue 1, January 2020, Pages 60-68

·       Glombiewski JA(1), Riecke J, Holzapfel S, Rief W, König S, Lachnit H, Seifart U. Do patients with chronic pain show autonomic arousal when confronted with feared movements? An experimental investigation of the fear-avoidance model. Pain. 2015 Jan 14.

·       Lubelski D1, Thompson NR, Bansal S, Mroz TE, Mazanec DJ, Benzel EC, Khalaf T. Depression as a predictor of worse quality of life outcomes following nonoperative treatment for lumbar stenosis. J Neurosurg Spine. 2014 Dec 19:1-6.

·       Kayhan F1, Albayrak Gezer İ2, Kayhan A3, Kitiş S4, Gölen M5. Mood and anxiety disorders in patients with chronic low back and neck pain caused by disc herniation. Int J Psychiatry Clin Pract. 2015 Nov 2:1-5. [Epub ahead of print]

·       Pillai AG, de Jong D, Kanatsou S, Krugers H, Knapman A, Heinzmann JM, Holsboer F,Landgraf R, Joëls M, Touma C. Dendritic morphology of hippocampal and amygdalar neurons in adolescent mice is resilient to genetic differences in stress reactivity. PLoS One. 2012;7(6):e38971. Epub 2012 Jun 12.